Collagen Biostimulator
Restore firmness, volume, and youthful radiance—naturally.
Collagen Biostimulators activate your skin’s own regenerative abilities, rebuilding structure from within for results that strengthen, lift, and refresh over time.
Unlike traditional fillers, these injectables stimulate long-term collagen production for subtle, natural-looking rejuvenation.
Treatment Overview
Collagen Biostimulators are injectable treatments that stimulate your skin’s natural collagen production to restore firmness, elasticity, and structure. Instead of adding volume, they activate fibroblasts beneath the skin, creating progressive, long-lasting rejuvenation that looks completely natural.
Using clinically proven ingredients like PLLA or CaHA, these treatments help the skin become firmer, thicker, and more lifted as new collagen forms. Ideal for clients wanting subtle, non-volumising enhancement, biostimulators target early sagging, laxity, and age-related collagen loss.
At Skinworks, we offer premium options such as Lenisna and PlaVann, customised to support tightening, contouring, and long-term skin quality.
Benefits
Long-Term Collagen Regeneration
Biostimulators stimulate your skin’s natural collagen-building process, improving firmness, elasticity, and structural strength for up to 12–24 months.
Natural, Progressive Rejuvenation
Results develop gradually, ensuring a refreshed, lifted appearance without the volume-heavy effect sometimes associated with fillers
Improved Skin Texture & Thickness
As collagen rebuilds, the skin becomes smoother, more resilient, and noticeably thicker, reducing the appearance of lines and early sagging.
Subtle Lifting & Contouring
Biostimulators help refine facial contours—especially the jawline, cheeks, and lower face—by restoring internal support structures.
Enhanced Hydration & Radiance
Hybrid formulations containing hyaluronic acid improve moisture levels and deliver an immediate healthy glow.
Long-Lasting Results
With a recommended series of treatments, results last 12–24 months, and yearly maintenance keeps collagen levels optimised over time.
Best Paired With
Collagen Biostimulators work beautifully alongside other advanced skin treatments to enhance results, improve overall skin quality, and target multiple layers of the skin simultaneously. When paired correctly, they create a more lifted, hydrated, and refined appearance with longer-lasting rejuvenation.
Dermapen Microneedling
Microneedling enhances collagen production at the superficial level while biostimulators rebuild deeper dermal layers—creating a powerful rejuvenation synergy.
Skin Boosters
Deep hydration treatments such as Prophilo or Nucleofill complement biostimulators by improving elasticity, luminosity, and skin quality while collagen is regenerating.
Botox
Softens dynamic wrinkles while biostimulators improve underlying structure, giving the face a smoother and more lifted appearance.
HIFU Skin Tightening
HIFU targets deeper tissue layers for lifting, while biostimulators rebuild collagen in the dermis—together providing improved firmness and contour definition.
Chemical Peels
Peels refine texture and brighten the skin’s surface, enhancing the visible effects of the deeper collagen remodelling stimulated by biostimulators.
Before & After Gallery
Aftercare
Do:
- Apply cool compresses if mild swelling occurs
- Keep the area clean and avoid touching injection points
- Stay hydrated to support collagen formation
- Sleep elevated the first night if swelling is present
- Use gentle skincare for 48 hours
- Protect your skin with SPF 50 daily
- Follow your recommended treatment plan for best collagen stimulation
Avoid:
- Vigorous exercise for 24 hours
- Saunas, steam rooms, hot yoga, or sunbeds for 48–72 hours
- Facial massages or pressure on the treated area for one week
- Makeup for 12 hours after treatment
- Anti-inflammatory medication unless medically necessary (may inhibit collagen response
Frequently Asked Questions
How do Collagen Biostimulators differ from fillers?
Fillers add instant volume, while biostimulators trigger gradual collagen production for natural, long-term rejuvenation.
When will I see results?
Most clients notice early improvements in 4–6 weeks, with full collagen remodeling at around 3–4 months.
How long do results last?
Results typically last 12–24 months depending on product choice and individual collagen response.
How many sessions will I need?
Most clients need 2–3 sessions spaced 4–6 weeks apart, plus yearly maintenance.
Is there downtime?
Downtime is minimal. Avoid heat and strenuous exercise for 24 hours.
Which areas can be treated?
Common areas include the face, neck, décolleté, and hands.
Are Collagen Biostimulators safe?
Yes. They are biocompatible and have an excellent safety profile.
Can I combine this with other treatments?
Yes — biostimulators pair beautifully with microneedling, skinboosters, Botox, and HIFU.
Who should avoid this treatment?
Clients who are pregnant, breastfeeding, or have infections should postpone treatment.
Do biostimulators replace fillers or Botox?
No — they complement them by restoring collagen while fillers add volume and Botox softens movement.
Pricing & Packages
COLLEGEN BIOSTIMULATORS — Long-Term Collagen Stimulation | R3500 – R6500 depending on product and treatment area.
Available Options:
Lenisna (PDLLA + HA) – Face & Neck
R6500 for 16ml (2–3 sessions recommended)Lenisna (PDLLA + HA) – Face OR Neck
R3300 for 8ml (2–3 sessions recommended)PlaVann (PLLA + HA) – Face / Neck / Hands
R3500 (2–3 sessions recommended)
Treatment Plans & Maintenance:
Most clients achieve optimal results with 2–3 sessions, spaced 4–6 weeks apart, followed by yearly maintenance.
What Our Clients Say
I had the best experience at Skinworks. Hanneske is so friendly, and she makes the experience so pain free. She gave me a lot of advice and I cannot wait for my next appointment.
5 Star Rating
Always a pleasure to visit Dr Hanneske. She handles each pasient with care whilst being professional and an expert in the field! Will recommend her to everyone!
5 Star Rating
Hanneske is nie net uitatekend in haar werk nie...Sy is 'n baie spesiale mense mens....vriendin. altyd so lekker wegbreek na haar pragtige praktyk!
Ready to love your reflection?
Book your consultation today with Dr Hanneske Steyn, advanced medical facial specialist.